Laboratory for Systems Biochemistry

Welcome to the Wühr Lab!

We aim to advance quantitative proteomics and integrate it with complementary approaches to elucidate principles of cellular organization at the systems level.

From left: Wess Ferguson, Alex Johnson, Meera Gupta, Easun Arunachalam, Vyas Pujari, Argit Marishta, Liza Shestoperova, Joe Crapse,
Martin Wühr, Felix Keber, Matthew Zhang, Ahmed Sherif, Miguel Iglesias, Andrea Mariossi, Edward Cruz, Gloria Bao, Alexander Luna, Aashna Parikh

Mooney, Eric, Patrick Suthers, Wheaton Schroeder, Hoang Dinh V, Xi Li, Yihui Shen, Tianxia Xiao, et al. (2025) 2025. “Metabolic Flux and Resource Balance in the Oleaginous Yeast Rhodotorula Toruloides.”. Metabolic Engineering. doi:10.1016/j.ymben.2025.11.012.

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Li, Xi, Daniel Weilandt, Felix Keber, Arjuna Subramanian, Shayne Loynes, Christopher Rao V, Yihui Shen, Martin Wühr, and Joshua Rabinowitz. (2025) 2025. “Lipid Accumulation in Nitrogen and Phosphorus-Limited Yeast Is Caused by Less Growth-Related Dilution.”. Metabolic Engineering. doi:10.1016/j.ymben.2025.08.010.

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Cruz, Edward R, Alex Johnson, Vyas Pujari, Qi Zhang, Thao Nguyen, Michael Stadlmeier, Jessica Wang, et al. (2025) 2025. “Expanding Targeted Instrumentation for Discovery Applications: Complement Reporter Ion Quantification With a Quadrupole-Ion Trap Instrument.”. Journal of Proteome Research. doi:10.1021/acs.jproteome.5c00356.

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Pujari, Vyas, Joseph Crapse, Connor Nisbet, Gloria Bao, Wessley Ferguson, Christopher M Hosfield, Michael Rosenblatt, Felix Keber, and Martin Wühr. (2025) 2025. “Synergistic Arg-C Ultra and Lys-C Digestion for Quantitative Proteomics”. BioRxiv. Cold Spring Harbor Laboratory. doi:10.1101/2025.07.15.664461.

2025_Pujari_Wuhr_bioRxiv